Urso Dose Calculator

Did you know that the right dose of Urso is driven by your weight? We have developed the Urso Dose Calculator as a guide to achieving the right dose for you.

  • VISUALLY CALCULATE & TRACK YOUR DOSE WITHOUT ANY EQUATIONS.
  • WEIGHTS ARE DISPLAYED IN METRIC & IMPERIAL.
  • HANDY REFERENCE WHEN DISCUSSING YOUR TREATMENT WITH A CLINICIAN.
  • IF YOUR WEIGHT CHANGES, YOU MAY NEED TO ALTER YOUR URSO DOSE*.
  • NEVER STOP OR ADJUST YOUR DOSE WITHOUT CONSULTING A CLINICIAN.

The Right Dose For You

Ursodeoxycholic Acid (also known as Urso or UDCA) is the only licensed first-line treatment for people with Primary Biliary Cholangitis (PBC), and it is absolutely vital that every single patient is on the right personalised dose.

Your dose has a direct relationship with your weight, this is extremely important as weight isn’t necessarily constant, and many of us will put on or lose some weight over time which can have a direct impact on optimal Urso response.

The best way to ensure your blood tests are normalised is to be on the right Urso dose for you. Published research** has shown that, for the majority of patients, response to Urso leads to a normal life expectancy. Data tells us that you are most likely to respond when taking the optimal dose (13-15mg/kg/day). Unfortunately, there are still many PBC patients on too low a dose which can have a number of serious implications.

At the PBC Foundation, we believe the sooner everyone is on the correct dose, the better. Not only can Urso response and normalisation of liver tests in PBC lead to normal life expectancy, but even patients who do not respond to Urso are found to have prognostic benefit from taking Urso every day.

Step 1. Weigh Yourself
Step 2. Find Your Weight
Step 3. Know Your Dose

Our Urso Dose Calculator has been developed to help you understand, check and track that your Urso dose is right for you and your weight. Download below and simply find your weight (displayed in Metric and Imperial) on the Urso Dose Calculator; your recommended daily dose is next to it on the dosing scale. Keep it handy for future reference, and/or when discussing your treatment with a clinician.

NOTES ABOUT YOUR DOSE:

Our Urso Dose Calculator has been designed as guidance for achieving the standard recommended dosage. In some clinical situations, your clinician may recommend a different dose. If you are not taking the recommended dose, we advise that you discuss with your clinician that you are on the right dose for you.

*Do not stop or adjust your dose of Ursodeoxycholic Acid without discussing this first with your clinician. Urso is recommended as a lifetime treatment in PBC, even if your liver results are normal you should not stop the treatment, this likely means it’s working!

**SOURCE: ‘European Association for Study of the Liver (EASL), PBC Guideline 2017’, ‘American Association of Study of Liver Diseases (AASLD)’, and ‘PBC Guidance 2018, and British Society of Gastroenterology (BSG) PBC Guideline 2018’.

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